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I have been taking methotrexate for about 2 years for my rheumatoid arthritis. The medication helps me to decrease pain significantly and it does control inflammation. Some time ago I stopped taking it for 2 months because I would be able to go on without it, but my symptoms returned so I started taking it again. Great medication.



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Lack of efficacy was the reason for discontinuation in the case of 32 patients (36 percent) in the group that received methotrexate alone and 40 patients (12 percent) in the groups that received infliximab plus methotrexate.

Orencia also appears to have a lower rate of infections, serious infections, serious adverse events, and infusion reactions than Remicade.

On Thursday my RA flared up to the point that I had to go to the emergency room to get relieve so I could get some sleep because the Aleve, Tylonal and sleep air medication that I took was not working.

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Exact Tests showed no significant differences in adherence between those who had MTX-related problems and those who did not.

With methotrexate use, improvement in or disease activity is usually detected in 3 to 6 weeks.

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After spending 1 month in hospital in May 2013 due to severe flare and after IV prednisone and azathioprine failed to work the last resort to bring the flare under control and avoid surgery was infliximab infusions.

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Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis.

Because long-term prednisone therapy is associated with a variety of harmful consequences, methotrexate represents an alternative treatment for patients who do not tolerate prednisone or in whom symptoms of Crohn's disease persist despite a moderately high dose of prednisone.

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Overall, 958 patients underwent randomization, of whom 956 patients received tofacitinib at a dose of 5 mg twice daily (373 patients), tofacitinib at a dose of 10 mg twice daily (397 patients), or methotrexate (186 patients) (Fig.

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